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Amino acid sequence conservation of the algesic MBP fragment is required for its interaction with CDK5 and function in pain

Neurotrauma frequently results in neuropathic pain. Our earlier studies revealed that peripheral neurotrauma-induced fragmentation of the myelin basic protein (MBP), a major component of the myelin sheath formed by Schwann cells, initiates a pain response from light touch stimuli (mechanical allodyn...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Chernov, Andrei V., Remacle, Albert G., Hullugundi, Swathi K., Cieplak, Piotr, Angert, Mila, Dolkas, Jennifer, Shubayev, Veronica I., Strongin, Alex Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288010/
https://ncbi.nlm.nih.gov/pubmed/30079618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14623
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