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A myelin basic protein fragment induces sexually dimorphic transcriptome signatures of neuropathic pain in mice

In the peripheral nerve, mechanosensitive axons are insulated by myelin, a multilamellar membrane formed by Schwann cells. Here, we offer first evidence that a myelin degradation product induces mechanical hypersensitivity and global transcriptomics changes in a sex-specific manner. Focusing on down...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chernov, Andrei V., Hullugundi, Swathi K., Eddinger, Kelly A., Dolkas, Jennifer, Remacle, Albert G., Angert, Mila, James, Brian P., Yaksh, Tony L., Strongin, Alex Y., Shubayev, Veronica I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397096/
https://ncbi.nlm.nih.gov/pubmed/32532796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013696
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