A sensitive and selective ELISA methodology quantifies a demyelination marker in experimental and clinical samples

Sciatic nerve chronic constriction injury (CCI) in rodents produces nerve demyelination via proteolysis of myelin basic protein (MBP), the major component of myelin sheath. Proteolysis releases the cryptic MBP epitope, a demyelination marker, which is hidden in the native MBP fold. It has never been...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Remacle, Albert G., Dolkas, Jennifer, Angert, Mila, Hullugundi, Swathi K., Chernov, Andrei V., Jones, R. Carter W., Shubayev, Veronica I., Strongin, Alex Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886741/
https://ncbi.nlm.nih.gov/pubmed/29428829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2018.02.002
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