A Myogenic Double-Reporter Human Pluripotent Stem Cell Line Allows Prospective Isolation of Skeletal Muscle Progenitors

Myogenic differentiation of human pluripotent stem cells (hPSCs) has been done by gene overexpression or directed differentiation. However, viral integration, long-term culture, and the presence of unwanted cells are the main obstacles. By using CRISPR/Cas9n, a double-reporter human embryonic stem c...

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Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Wu, Jianbo, Matthias, Nadine, Lo, Jonathan, Ortiz-Vitali, Jose L., Shieh, Annie W., Wang, Sidney H., Darabi, Radbod
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287935/
https://ncbi.nlm.nih.gov/pubmed/30428361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.067
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