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A Myogenic Double-Reporter Human Pluripotent Stem Cell Line Allows Prospective Isolation of Skeletal Muscle Progenitors

Myogenic differentiation of human pluripotent stem cells (hPSCs) has been done by gene overexpression or directed differentiation. However, viral integration, long-term culture, and the presence of unwanted cells are the main obstacles. By using CRISPR/Cas9n, a double-reporter human embryonic stem c...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wu, Jianbo, Matthias, Nadine, Lo, Jonathan, Ortiz-Vitali, Jose L., Shieh, Annie W., Wang, Sidney H., Darabi, Radbod
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287935/
https://ncbi.nlm.nih.gov/pubmed/30428361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.067
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