Mechanisms underlying prelimbic prefrontal cortex mGlu(3)/mGlu(5)-dependent plasticity and reversal learning deficits following acute stress

Stress can precipitate or worsen symptoms of many psychiatric illnesses. Dysregulation of the prefrontal cortex (PFC) glutamate system may underlie these disruptions and restoring PFC glutamate signaling has emerged as a promising avenue for the treatment of stress disorders. Recently, we demonstrat...

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Publicado en:Neuropharmacology
Autores principales: Joffe, Max E., Santiago, Chiaki I., Stansley, Branden J., Maksymetz, James, Gogliotti, Rocco G., Engers, Julie L., Nicoletti, Ferdinando, Lindsley, Craig W., Conn, P. Jeffrey
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286225/
https://ncbi.nlm.nih.gov/pubmed/30326237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.10.013
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