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A splice variant of human Bmal1 acts as a negative regulator of the molecular circadian clock

Bmal1 is one of the key molecules that controls the mammalian molecular clock. In humans, two isoforms of Bmal1 are generated by alternative RNA splicing. Unlike the extensively studied hBmal1b, the canonical form of Bmal1 in most species, the expression and/or function of another human-specific iso...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Lee, Jiwon, Park, Eonyoung, Kim, Ga Hye, Kwon, Ilmin, Kim, Kyungjin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283877/
https://ncbi.nlm.nih.gov/pubmed/30523262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0187-x
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