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A splice variant of human Bmal1 acts as a negative regulator of the molecular circadian clock

Bmal1 is one of the key molecules that controls the mammalian molecular clock. In humans, two isoforms of Bmal1 are generated by alternative RNA splicing. Unlike the extensively studied hBmal1b, the canonical form of Bmal1 in most species, the expression and/or function of another human-specific iso...

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Publicado en:Exp Mol Med
Autores principales: Lee, Jiwon, Park, Eonyoung, Kim, Ga Hye, Kwon, Ilmin, Kim, Kyungjin
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283877/
https://ncbi.nlm.nih.gov/pubmed/30523262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0187-x
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