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A splice variant of human Bmal1 acts as a negative regulator of the molecular circadian clock

Bmal1 is one of the key molecules that controls the mammalian molecular clock. In humans, two isoforms of Bmal1 are generated by alternative RNA splicing. Unlike the extensively studied hBmal1b, the canonical form of Bmal1 in most species, the expression and/or function of another human-specific iso...

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Détails bibliographiques
Publié dans:Exp Mol Med
Auteurs principaux: Lee, Jiwon, Park, Eonyoung, Kim, Ga Hye, Kwon, Ilmin, Kim, Kyungjin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283877/
https://ncbi.nlm.nih.gov/pubmed/30523262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0187-x
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