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Dual Modification of BMAL1 by SUMO2/3 and Ubiquitin Promotes Circadian Activation of the CLOCK/BMAL1 Complex

Heterodimers of BMAL1 and CLOCK drive rhythmic expression of clock-controlled genes, thereby generating circadian physiology and behavior. Posttranslational modifications of BMAL1 play a key role in modulating the transcriptional activity of the CLOCK/BMAL1 complex during the circadian cycle. Recent...

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Bibliografski detalji
Glavni autori: Lee, Jiwon, Lee, Yool, Lee, Min Joo, Park, Eonyoung, Kang, Sung Hwan, Chung, Chin Ha, Lee, Kun Ho, Kim, Kyungjin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546997/
https://ncbi.nlm.nih.gov/pubmed/18644859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00583-08
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