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BMAL1 Shuttling Controls Transactivation and Degradation of the CLOCK/BMAL1 Heterodimer
CLOCK and BMAL1 are bHLH-PAS-containing transcription factors that bind to E-box elements and are indispensable for expression of core circadian clock components such as the Per and Cry genes. A key step in expression is the heterodimerization of CLOCK and BMAL1 and their accumulation in the nucleus...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592876/ https://ncbi.nlm.nih.gov/pubmed/16980631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00337-06 |
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