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Structural insight into substrate and product binding in an archaeal mevalonate kinase

Mevalonate kinase (MK) is a key enzyme of the mevalonate pathway, which produces the biosynthetic precursors for steroids, including cholesterol, and isoprenoids, the largest class of natural products. Currently available crystal structures of MK from different organisms depict the enzyme in its unb...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Miller, Bradley R., Kung, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283576/
https://ncbi.nlm.nih.gov/pubmed/30521590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208419
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