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Structural insight into substrate and product binding in an archaeal mevalonate kinase

Mevalonate kinase (MK) is a key enzyme of the mevalonate pathway, which produces the biosynthetic precursors for steroids, including cholesterol, and isoprenoids, the largest class of natural products. Currently available crystal structures of MK from different organisms depict the enzyme in its unb...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Miller, Bradley R., Kung, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283576/
https://ncbi.nlm.nih.gov/pubmed/30521590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208419
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