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Structural and mechanistic insight into covalent substrate binding by Escherichia coli dihydroxyacetone kinase

The Escherichia coli dihydroxyacetone (Dha) kinase is an unusual kinase because (i) it uses the phosphoenolpyruvate carbohydrate: phosphotransferase system (PTS) as the source of high-energy phosphate, (ii) the active site is formed by two subunits, and (iii) the substrate is covalently bound to His...

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Detalhes bibliográficos
Main Authors: Shi, Rong, McDonald, Laura, Cui, Qizhi, Matte, Allan, Cygler, Miroslaw, Ekiel, Irena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029771/
https://ncbi.nlm.nih.gov/pubmed/21209328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012596108
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