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Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase

BACKGROUND: Isoprenoid precursor synthesis via the mevalonate route in humans and pathogenic trypanosomatids is an important metabolic pathway. There is however, only limited information available on the structure and reactivity of the component enzymes in trypanosomatids. Since isoprenoid biosynthe...

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Detalhes bibliográficos
Main Authors: Sgraja, Tanja, Smith, Terry K, Hunter, William N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851959/
https://ncbi.nlm.nih.gov/pubmed/17397541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-20
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