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Structure and reactivity of LpxD, the N-acyltransferase of lipid A biosynthesis

The external layer of the Gram-negative bacterial outer membrane is primarily composed of a protective, selectively permeable LPS. The biosynthesis of LPS relies on UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD), which transfers 3-hydroxy-arachidic acid from acyl carrier protein to the 2′ amine o...

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Autori principali: Buetow, Lori, Smith, Terry K., Dawson, Alice, Fyffe, Stewart, Hunter, William N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810333/
https://ncbi.nlm.nih.gov/pubmed/17360522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606356104
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