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Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate
DNA conformation may deviate from the classical B-form in ∼13% of the human genome. Non-B DNA regulates many cellular processes; however, its effects on DNA polymerization speed and accuracy have not been investigated genome-wide. Such an inquiry is critical for understanding neurological diseases a...
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| Pubblicato in: | Genome Res |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6280752/ https://ncbi.nlm.nih.gov/pubmed/30401733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.241257.118 |
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