Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate

DNA conformation may deviate from the classical B-form in ∼13% of the human genome. Non-B DNA regulates many cellular processes; however, its effects on DNA polymerization speed and accuracy have not been investigated genome-wide. Such an inquiry is critical for understanding neurological diseases a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Guiblet, Wilfried M., Cremona, Marzia A., Cechova, Monika, Harris, Robert S., Kejnovská, Iva, Kejnovsky, Eduard, Eckert, Kristin, Chiaromonte, Francesca, Makova, Kateryna D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280752/
https://ncbi.nlm.nih.gov/pubmed/30401733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.241257.118
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados