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Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome
Approximately 1% of the human genome has the ability to fold into G-quadruplexes (G4s)—noncanonical strand-specific DNA structures forming at G-rich motifs. G4s regulate several key cellular processes (e.g., transcription) and have been hypothesized to participate in others (e.g., firing of replicat...
Gespeichert in:
| Veröffentlicht in: | Genome Res |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8256861/ https://ncbi.nlm.nih.gov/pubmed/34187812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.269589.120 |
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