TNFR2/BIRC3-TRAF1 signaling pathway as a novel NK cell immune checkpoint in cancer

Natural Killer (NK) cells control metastatic dissemination of murine tumors and are an important prognostic factor in several human malignancies. However, tumor cells hijack many of the NK cell functional features compromising their tumoricidal activity. Here, we show a deleterious role of the TNFα/...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Ivagnès, Alexandre, Messaoudene, Meriem, Stoll, Gautier, Routy, Bertrand, Fluckiger, Aurélie, Yamazaki, Takahiro, Iribarren, Kristina, Duong, Connie P. M., Fend, Laetitia, Caignard, Anne, Cremer, Isabelle, LeCesne, Axel, Adam, Julien, Honoré, Charles, Mir, Olivier, Chaigneau, Loïc, Berger, Anne, Validire, Pierre, Christidis, Christos, Brun-Ly, Valérie Le, Smyth, Mark J., Mariette, Xavier, Salomon, Benoît L., Kroemer, Guido, Rusakiewicz, Sylvie, Zitvogel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279330/
https://ncbi.nlm.nih.gov/pubmed/30524877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1386826
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