A TRAF2 binding independent region of TNFR2 is responsibl for TRAF2 depletion and enhancement of cytotoxicity driven b TNFR1

Tumor Necrosis Factor (TNF) interacts with two receptors known as TNFR1 and TNFR2. TNFR1 activation may result in either cell proliferation or cell death. TNFR2 activates Nuclear Factor-kappaB (NF-kB) and c-Jun N-terminal kinase (JNK) which lead to transcriptional activation of genes related to cell...

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Detalhes bibliográficos
Main Authors: Cabal-Hierro, Lucía, Noelia, Artime, Iglesias, Julián, Miguel A., Prado, Ugarte-Gil, Lore, Pedro, Casado, Fernández-García, Belén, Darnay, Bryant G., Lazo, Pedro S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960203/
https://ncbi.nlm.nih.gov/pubmed/24318359
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