TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs

TNF family members and their receptors contribute to increased gene expression for inflammatory processes and intracellular cascades leading to programmed cell death, both via activation of NF-κB. TNF receptor (TNFR)-associated factors (TRAFs) are cytoplasmic adaptor proteins binding to various rece...

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Bibliographische Detailangaben
Hauptverfasser: Hauer, Julia, Püschner, Stephanie, Ramakrishnan, Parameswaran, Simon, Ute, Bongers, Martina, Federle, Christine, Engelmann, Hartmut
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549490/
https://ncbi.nlm.nih.gov/pubmed/15708970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500187102
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