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Sam68 is Required for both NF-κB Activation and Apoptosis Signaling by the TNF receptor

The RNA binding protein Sam68 is implicated in various cellular processes including RNA metabolism, apoptosis and signal transduction. Here we identify a role of Sam68 in TNF-induced NF-κB activation and apoptosis. We found that Sam68 is recruited to the TNF receptor and its deficiency dramatically...

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Detalhes bibliográficos
Main Authors: Ramakrishnan, Parameswaran, Baltimore, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142289/
https://ncbi.nlm.nih.gov/pubmed/21620750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.007
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