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Sam68 is Required for both NF-κB Activation and Apoptosis Signaling by the TNF receptor
The RNA binding protein Sam68 is implicated in various cellular processes including RNA metabolism, apoptosis and signal transduction. Here we identify a role of Sam68 in TNF-induced NF-κB activation and apoptosis. We found that Sam68 is recruited to the TNF receptor and its deficiency dramatically...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142289/ https://ncbi.nlm.nih.gov/pubmed/21620750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.007 |
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