TNFR2/BIRC3-TRAF1 signaling pathway as a novel NK cell immune checkpoint in cancer

Natural Killer (NK) cells control metastatic dissemination of murine tumors and are an important prognostic factor in several human malignancies. However, tumor cells hijack many of the NK cell functional features compromising their tumoricidal activity. Here, we show a deleterious role of the TNFα/...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Ivagnès, Alexandre, Messaoudene, Meriem, Stoll, Gautier, Routy, Bertrand, Fluckiger, Aurélie, Yamazaki, Takahiro, Iribarren, Kristina, Duong, Connie P. M., Fend, Laetitia, Caignard, Anne, Cremer, Isabelle, LeCesne, Axel, Adam, Julien, Honoré, Charles, Mir, Olivier, Chaigneau, Loïc, Berger, Anne, Validire, Pierre, Christidis, Christos, Brun-Ly, Valérie Le, Smyth, Mark J., Mariette, Xavier, Salomon, Benoît L., Kroemer, Guido, Rusakiewicz, Sylvie, Zitvogel, Laurence
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279330/
https://ncbi.nlm.nih.gov/pubmed/30524877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1386826
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