Загрузка...
A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold
A key step in nutrient sensing is the activation of the master growth regulator, mTORC1 kinase, on the surface of lysosomes. Nutrients enable mTORC1 scaffolding by a complex composed of the Rag GTPases (Rags) and Ragulator, but the underlying mechanism of mTORC1 capture is poorly understood. Combini...
Сохранить в:
| Опубликовано в: : | Nat Cell Biol |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6279252/ https://ncbi.nlm.nih.gov/pubmed/30061680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0148-6 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|