mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model

The rising incidence of human papillomavirus (HPV)-associated malignancies, especially for oropharyngeal cancers, has highlighted the urgent need to understand how the interplay between high-risk HPV oncogenes and carcinogenic exposure results in squamous cell carcinoma (SCC) development. Here, we d...

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Publicat a:Carcinogenesis
Autors principals: Callejas-Valera, Juan Luis, Iglesias-Bartolome, Ramiro, Amornphimoltham, Panomwat, Palacios-Garcia, Julia, Martin, Daniel, Califano, Joseph A., Molinolo, Alfredo A., Gutkind, J.Silvio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Original Manuscript
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276901/
https://ncbi.nlm.nih.gov/pubmed/27538837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw086
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