Engineered RNase P Ribozymes Effectively Inhibit the Infection of Murine Cytomegalovirus in Animals

Rationales: Gene-targeting ribozymes represent promising nucleic acid-based gene interference agents for therapeutic application. We previously used an in vitro selection procedure to engineer novel RNase P-based ribozyme variants with enhanced targeting activity. However, it has not been reported w...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Li, Wei, Liu, Yujun, Wang, Yuanyuan, Li, Ruilin, Trang, Phong, Tang, Wei, Yang, Zhu, Wang, Yu, Sun, Xu, Xing, Xiwen, Lu, Sangwei, Liu, Fenyong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276291/
https://ncbi.nlm.nih.gov/pubmed/30555569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.27776
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