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RNase P ribozyme inhibits cytomegalovirus replication by blocking the expression of viral capsid proteins
By linking a guide sequence to the catalytic RNA subunit of RNase P (M1 RNA), we constructed a functional ribozyme (M1GS RNA) that targets the overlapping mRNA region of two human cytomegalovirus (HCMV) capsid proteins, the capsid scaffolding protein (CSP) and assemblin, which are essential for vira...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC443536/ https://ncbi.nlm.nih.gov/pubmed/15220469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh660 |
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