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RNase P ribozyme inhibits cytomegalovirus replication by blocking the expression of viral capsid proteins
By linking a guide sequence to the catalytic RNA subunit of RNase P (M1 RNA), we constructed a functional ribozyme (M1GS RNA) that targets the overlapping mRNA region of two human cytomegalovirus (HCMV) capsid proteins, the capsid scaffolding protein (CSP) and assemblin, which are essential for vira...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh660 |
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