Antileukemic activity of combined epigenetic agents, DNMT inhibitors zebularine and RG108 with HDAC inhibitors, against promyelocytic leukemia HL-60 cells

DNMT inhibitors are promising new drugs for cancer therapies. In this study, we have observed the antileukemic action of two diverse DNMT inhibitors, the nucleoside agent zebularine and the non-nucleoside agent RG108, in human promyelocytic leukemia (PML) HL-60 cells. Zebularine but not RG108 caused...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Mol Biol Lett
Autors principals: Savickiene, Jurate, Treigyte, Grazina, Borutinskaite, Veronika-Viktorija, Navakauskiene, Ruta
Format: Artigo
Idioma:Inglês
Publicat: SP Versita 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275587/
https://ncbi.nlm.nih.gov/pubmed/22820861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-012-0024-5
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars