Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy

Human amniotic-fluid-derived mesenchymal stem cells (AF-MSCs) are interesting for their multilineage differentiation potential and wide range of therapeutic applications due to the ease of culture expansion. However, MSCs undergo replicative senescence. So far, the molecular mechanisms that underlie...

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Publicat a:Stem Cells Int
Autors principals: Savickienė, Jūratė, Baronaitė, Sandra, Zentelytė, Aistė, Treigytė, Gražina, Navakauskienė, Rūta
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075644/
https://ncbi.nlm.nih.gov/pubmed/27803714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2019498
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