Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy

Human amniotic-fluid-derived mesenchymal stem cells (AF-MSCs) are interesting for their multilineage differentiation potential and wide range of therapeutic applications due to the ease of culture expansion. However, MSCs undergo replicative senescence. So far, the molecular mechanisms that underlie...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Savickienė, Jūratė, Baronaitė, Sandra, Zentelytė, Aistė, Treigytė, Gražina, Navakauskienė, Rūta
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075644/
https://ncbi.nlm.nih.gov/pubmed/27803714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2019498
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