HDAC and HMT Inhibitors in Combination with Conventional Therapy: A Novel Treatment Option for Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is characterized by PML-RARA translocation, which causes the blockage of promyelocyte differentiation. Conventional treatment with Retinoic acid and chemotherapeutics is quite satisfactory. However, there are still patients who relapse or develop resistance to conv...

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Publicat a:J Oncol
Autors principals: Vitkevičienė, Aida, Skiauterytė, Giedrė, Žučenka, Andrius, Stoškus, Mindaugas, Gineikienė, Eglė, Borutinskaitė, Veronika, Griškevičius, Laimonas, Navakauskienė, Rūta
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668531/
https://ncbi.nlm.nih.gov/pubmed/31396278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6179573
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