HDAC and HMT Inhibitors in Combination with Conventional Therapy: A Novel Treatment Option for Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is characterized by PML-RARA translocation, which causes the blockage of promyelocyte differentiation. Conventional treatment with Retinoic acid and chemotherapeutics is quite satisfactory. However, there are still patients who relapse or develop resistance to conv...

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Detalhes bibliográficos
Publicado no:J Oncol
Main Authors: Vitkevičienė, Aida, Skiauterytė, Giedrė, Žučenka, Andrius, Stoškus, Mindaugas, Gineikienė, Eglė, Borutinskaitė, Veronika, Griškevičius, Laimonas, Navakauskienė, Rūta
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668531/
https://ncbi.nlm.nih.gov/pubmed/31396278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6179573
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