HDAC and HMT Inhibitors in Combination with Conventional Therapy: A Novel Treatment Option for Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is characterized by PML-RARA translocation, which causes the blockage of promyelocyte differentiation. Conventional treatment with Retinoic acid and chemotherapeutics is quite satisfactory. However, there are still patients who relapse or develop resistance to conv...

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Bibliografske podrobnosti
izdano v:J Oncol
Main Authors: Vitkevičienė, Aida, Skiauterytė, Giedrė, Žučenka, Andrius, Stoškus, Mindaugas, Gineikienė, Eglė, Borutinskaitė, Veronika, Griškevičius, Laimonas, Navakauskienė, Rūta
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668531/
https://ncbi.nlm.nih.gov/pubmed/31396278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6179573
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