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The Histone Deacetylase Inhibitor BML-210 Influences Gene and Protein Expression in Human Promyelocytic Leukemia NB4 Cells via Epigenetic Reprogramming

Today, cancer is understood as an epigenetic as well as genetic disease. The main epigenetic hallmarks of the cancer cell are DNA methylation and histone modifications. Proteins such as histone deacetylases (HDACs) that cause modifications of histones and other proteins can be targets for novel anti...

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Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Borutinskaitė, Veronika, Navakauskienė, Rūta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581243/
https://ncbi.nlm.nih.gov/pubmed/26287160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160818252
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