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Targeting Epigenetics through Histone Deacetylase Inhibitors in Acute Lymphoblastic Leukemia

Epigenetics play a critical role in controlling normal gene expression and altered epigenetics can lead to abnormal cellular differentiation, proliferation and survival. Acute lymphoblastic leukemia (ALL) is the most common malignancy in children and is characterized by numerous epigenetic abnormali...

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Detalhes bibliográficos
Main Authors: Mummery, A., Narendran, A., Lee, K.-Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855493/
https://ncbi.nlm.nih.gov/pubmed/21762078
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