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Thymic epithelial cell support of thymopoiesis does not require Klotho
Age-related thymic involution is characterized by a decrease in thymic epithelial cell (TEC) number and function parallel to a disruption in their spatial organization, resulting in defective thymocyte development and proliferation as well as peripheral T cell dysfunction. Deficiency of Klotho, an a...
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| Publié dans: | J Immunol |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6275142/ https://ncbi.nlm.nih.gov/pubmed/30373854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800670 |
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