T cell progenitor therapy–facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

Infusion of in vitro–derived T cell progenitor (proT) therapy with hematopoietic stem cell transplant aids the recovery of the thymus damaged by total body irradiation. To understand the interaction between proTs and the thymic microenvironment, WT mice were lethally irradiated and given T cell–defi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Smith, Michelle J., Reichenbach, Dawn K., Parker, Sarah L., Riddle, Megan J., Mitchell, Jason, Osum, Kevin C., Mohtashami, Mahmood, Stefanski, Heather E., Fife, Brian T., Bhandoola, Avinash, Hogquist, Kristin A., Holländer, Georg A., Zúñiga-Pflücker, Juan Carlos, Tolar, Jakub, Blazar, Bruce R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436538/
https://ncbi.nlm.nih.gov/pubmed/28515359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92056
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