T cell progenitor therapy–facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

Infusion of in vitro–derived T cell progenitor (proT) therapy with hematopoietic stem cell transplant aids the recovery of the thymus damaged by total body irradiation. To understand the interaction between proTs and the thymic microenvironment, WT mice were lethally irradiated and given T cell–defi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Smith, Michelle J., Reichenbach, Dawn K., Parker, Sarah L., Riddle, Megan J., Mitchell, Jason, Osum, Kevin C., Mohtashami, Mahmood, Stefanski, Heather E., Fife, Brian T., Bhandoola, Avinash, Hogquist, Kristin A., Holländer, Georg A., Zúñiga-Pflücker, Juan Carlos, Tolar, Jakub, Blazar, Bruce R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436538/
https://ncbi.nlm.nih.gov/pubmed/28515359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92056
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