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Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development

MicroRNAs (miRNAs) have been shown to be key modulators of post-transcriptional gene silencing in many cellular processes. In previous studies designed to understand the role of miRNAs in thymic development, we globally deleted miRNA exclusively in thymic epithelial cells (TECs), which are critical...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stefanski, Heather E., Xing, Yan, Taylor, Patricia A., Maio, Stefano, Henao-Meija, Jorge, Williams, Adam, Flavell, Richard A., Hollander, Georg A., Blazar, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021062/
https://ncbi.nlm.nih.gov/pubmed/29949604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198871
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