miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

The interdependence of selective cues during development of regulatory T cells (Treg cells) in the thymus and their suppressive function remains incompletely understood. Here, we analyzed this interdependence by taking advantage of highly dynamic changes in expression of microRNA 181 family members...

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Publicado en:PLoS Biol
Main Authors: Łyszkiewicz, Marcin, Winter, Samantha J., Witzlau, Katrin, Föhse, Lisa, Brownlie, Rebecca, Puchałka, Jacek, Verheyden, Nikita A., Kunze-Schumacher, Heike, Imelmann, Esther, Blume, Jonas, Raha, Solaiman, Sekiya, Takashi, Yoshimura, Akihiko, Frueh, Jochen T., Ullrich, Evelyn, Huehn, Jochen, Weiss, Siegfried, Gutierrez, Maximiliano G., Prinz, Immo, Zamoyska, Rose, Ziętara, Natalia, Krueger, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428341/
https://ncbi.nlm.nih.gov/pubmed/30856173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006716
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