miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

The interdependence of selective cues during development of regulatory T cells (Treg cells) in the thymus and their suppressive function remains incompletely understood. Here, we analyzed this interdependence by taking advantage of highly dynamic changes in expression of microRNA 181 family members...

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Bibliografske podrobnosti
izdano v:PLoS Biol
Main Authors: Łyszkiewicz, Marcin, Winter, Samantha J., Witzlau, Katrin, Föhse, Lisa, Brownlie, Rebecca, Puchałka, Jacek, Verheyden, Nikita A., Kunze-Schumacher, Heike, Imelmann, Esther, Blume, Jonas, Raha, Solaiman, Sekiya, Takashi, Yoshimura, Akihiko, Frueh, Jochen T., Ullrich, Evelyn, Huehn, Jochen, Weiss, Siegfried, Gutierrez, Maximiliano G., Prinz, Immo, Zamoyska, Rose, Ziętara, Natalia, Krueger, Andreas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428341/
https://ncbi.nlm.nih.gov/pubmed/30856173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006716
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