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Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

Age-related thymopoietic insufficiency has been proposed to be related to either defects in lymphohematopoietic progenitors or the thymic microenvironment. In this study, we examined whether keratinocyte growth factor (KGF), an epithelial cell–specific growth factor, could increase thymopoietic capa...

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Detalhes bibliográficos
Main Authors: Min, Dullei, Panoskaltsis-Mortari, Angela, Kuro-o, Makoto, Holländer, Georg A., Blazar, Bruce R., Weinberg, Kenneth I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852207/
https://ncbi.nlm.nih.gov/pubmed/17138819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-08-043794
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