Non-Coding Micro RNAs and Hypoxia-Inducible Factors Are Selenium Targets for Development of a Mechanism-Based Combination Strategy in Clear-Cell Renal Cell Carcinoma—Bench-to-Bedside Therapy

Durable response, inherent or acquired resistance, and dose-limiting toxicities continue to represent major barriers in the treatment of patients with advanced clear-cell renal cell carcinoma (ccRCC). The majority of ccRCC tumors are characterized by the loss of Von Hippel–Lindau tumor suppressor ge...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Rustum, Youcef M., Chintala, Sreenivasulu, Durrani, Farukh A., Bhattacharya, Arup
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275006/
https://ncbi.nlm.nih.gov/pubmed/30380599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113378
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