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Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase

Fatty Acid Amide Hydrolase (FAAH) is an intracellular serine enzyme involved in the biological degradation of the fatty acid ethanolamide family of signaling lipids, which exerts neuroprotective, anti-inflammatory, and analgesic properties. In the present study, a conjugated 2,4-dioxo-pyrimidine-1-c...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Qiu, Yan, Zhang, Yang, Li, Yuhang, Ren, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274076/
https://ncbi.nlm.nih.gov/pubmed/26901181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020229
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