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Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase

Fatty Acid Amide Hydrolase (FAAH) is an intracellular serine enzyme involved in the biological degradation of the fatty acid ethanolamide family of signaling lipids, which exerts neuroprotective, anti-inflammatory, and analgesic properties. In the present study, a conjugated 2,4-dioxo-pyrimidine-1-c...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Qiu, Yan, Zhang, Yang, Li, Yuhang, Ren, Jie
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274076/
https://ncbi.nlm.nih.gov/pubmed/26901181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020229
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