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Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase

Fatty Acid Amide Hydrolase (FAAH) is an intracellular serine enzyme involved in the biological degradation of the fatty acid ethanolamide family of signaling lipids, which exerts neuroprotective, anti-inflammatory, and analgesic properties. In the present study, a conjugated 2,4-dioxo-pyrimidine-1-c...

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書目詳細資料
發表在:Molecules
Main Authors: Qiu, Yan, Zhang, Yang, Li, Yuhang, Ren, Jie
格式: Artigo
語言:Inglês
出版: MDPI 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274076/
https://ncbi.nlm.nih.gov/pubmed/26901181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020229
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