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Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase

Fatty Acid Amide Hydrolase (FAAH) is an intracellular serine enzyme involved in the biological degradation of the fatty acid ethanolamide family of signaling lipids, which exerts neuroprotective, anti-inflammatory, and analgesic properties. In the present study, a conjugated 2,4-dioxo-pyrimidine-1-c...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Qiu, Yan, Zhang, Yang, Li, Yuhang, Ren, Jie
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274076/
https://ncbi.nlm.nih.gov/pubmed/26901181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21020229
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