Carregant...
Drug-Induced Conformational Population Shifts in Topoisomerase-DNA Ternary Complexes
Type II topoisomerases (TOP2) are enzymes that resolve the topological problems during DNA replication and transcription by transiently cleaving both strands and forming a cleavage complex with the DNA. Several prominent anti-cancer agents inhibit TOP2 by stabilizing the cleavage complex and engende...
Guardat en:
| Publicat a: | Molecules |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2014
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6272011/ https://ncbi.nlm.nih.gov/pubmed/24905608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19067415 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|