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Nilotinib Enhances the Efficacy of Conventional Chemotherapeutic Drugs in CD34(+)CD38(−) Stem Cells and ABC Transporter Overexpressing Leukemia Cells

Incomplete chemotherapeutic eradication of leukemic CD34(+)CD38(−) stem cells is likely to result in disease relapse. The purpose of this study was to evaluate the effect of nilotinib on eradicating leukemia stem cells and enhancing the efficacy of chemotherapeutic agents. Our results showed that AB...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wang, Fang, Wang, Xiao-Kun, Shi, Cheng-Jun, Zhang, Hui, Hu, Ya-Peng, Chen, Yi-Fan, Fu, Li-Wu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270868/
https://ncbi.nlm.nih.gov/pubmed/24651611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19033356
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