Nilotinib Enhances the Efficacy of Conventional Chemotherapeutic Drugs in CD34(+)CD38(−) Stem Cells and ABC Transporter Overexpressing Leukemia Cells

Incomplete chemotherapeutic eradication of leukemic CD34(+)CD38(−) stem cells is likely to result in disease relapse. The purpose of this study was to evaluate the effect of nilotinib on eradicating leukemia stem cells and enhancing the efficacy of chemotherapeutic agents. Our results showed that AB...

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Vydáno v:Molecules
Hlavní autoři: Wang, Fang, Wang, Xiao-Kun, Shi, Cheng-Jun, Zhang, Hui, Hu, Ya-Peng, Chen, Yi-Fan, Fu, Li-Wu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270868/
https://ncbi.nlm.nih.gov/pubmed/24651611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19033356
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