Phenotyping and Target Expression Profiling of CD34(+)/CD38(−) and CD34(+)/CD38(+) Stem- and Progenitor cells in Acute Lymphoblastic Leukemia

Leukemic stem cells (LSCs) are an emerging target of curative anti-leukemia therapy. In acute lymphoblastic leukemia (ALL), LSCs frequently express CD34 and often lack CD38. However, little is known about markers and targets expressed in ALL LSCs. We have examined marker- and target expression profi...

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Bibliografiske detaljer
Udgivet i:Neoplasia
Main Authors: Blatt, Katharina, Menzl, Ingeborg, Eisenwort, Gregor, Cerny-Reiterer, Sabine, Herrmann, Harald, Herndlhofer, Susanne, Stefanzl, Gabriele, Sadovnik, Irina, Berger, Daniela, Keller, Alexandra, Hauswirth, Alexander, Hoermann, Gregor, Willmann, Michael, Rülicke, Thomas, Sill, Heinz, Sperr, Wolfgang R., Mannhalter, Christine, Melo, Junia V., Jäger, Ulrich, Sexl, Veronika, Valent, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2018
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Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994777/
https://ncbi.nlm.nih.gov/pubmed/29772458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.04.004
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