Phenotyping and Target Expression Profiling of CD34(+)/CD38(−) and CD34(+)/CD38(+) Stem- and Progenitor cells in Acute Lymphoblastic Leukemia

Leukemic stem cells (LSCs) are an emerging target of curative anti-leukemia therapy. In acute lymphoblastic leukemia (ALL), LSCs frequently express CD34 and often lack CD38. However, little is known about markers and targets expressed in ALL LSCs. We have examined marker- and target expression profi...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Blatt, Katharina, Menzl, Ingeborg, Eisenwort, Gregor, Cerny-Reiterer, Sabine, Herrmann, Harald, Herndlhofer, Susanne, Stefanzl, Gabriele, Sadovnik, Irina, Berger, Daniela, Keller, Alexandra, Hauswirth, Alexander, Hoermann, Gregor, Willmann, Michael, Rülicke, Thomas, Sill, Heinz, Sperr, Wolfgang R., Mannhalter, Christine, Melo, Junia V., Jäger, Ulrich, Sexl, Veronika, Valent, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2018
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994777/
https://ncbi.nlm.nih.gov/pubmed/29772458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.04.004
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